Serological Diagnosis of Autoimmune Blistering Diseases
نویسندگان
چکیده
منابع مشابه
Diagnosis and classification of autoimmune blistering diseases.
Blistering skin diseases are a group of autoimmune disorders that are characterized by autoantibodies against structural proteins of the epidermis or the dermal-epidermal junction and clinically by blisters and erosions on skin and/or mucous membranes. Since clinical criteria and histopathological characteristics are not sufficient for diagnosis, direct immunofluorescence microscopy of a biopsy...
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Abstract Introduction: In patients with autoimmune skin blistering diseases (ABDs), the diagnostic gold standard has classically been direct and indirect immunofluorescence (DIF and IIF), despite inherent technical problems of autofluorescence. Aim: We sought to overcome autofluorescence issues and compare the reliability of immunofluorescence versus immunohistochemistry (IHC) staining in the d...
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The autoimmune blistering diseases (AIBDs) are a group of heterogeneous skin diseases with autoantibodies directed against structural proteins in the skin. A new interest in the female bias towards autoimmune diseases in general has led to our attention to focus on how and why this female bias manifests in AIBD. The authors aim to review and explore the various aspects of AIBD affecting females...
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Blister formation in skin and mucous membranes results from a loss of cell-cell or cell-matrix adhesion and is a common outcome of pathological events in a variety of conditions, including autoimmune and genetic diseases, viral and bacterial infections, or injury by physical and chemical factors. Autoantibodies against structural components maintaining cell-cell and cell-matrix adhesion induce ...
متن کاملImmunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience*
BACKGROUND Immunofluorescence testing is an important tool for diagnosing blistering diseases. OBJECTIVE To characterize the immunofluorescence findings in patients diagnosed with autoimmune blistering skin diseases. METHODS We retrospectively analyzed immunofluorescence results encompassing a 10-year period. RESULTS 421 patients were included and divided into 2 groups: group 1- intraepid...
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ژورنال
عنوان ژورنال: Turkish Journal of Dermatology / Türk Dermatoloji Dergisi
سال: 2016
ISSN: 1307-7635
DOI: 10.4274/tdd.2016.10.01.01